apalutamide will lower the level or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a strong CYP2C19 inducer, with medicine which are CYP2C19 substrates may result in decreased publicity to these drugs.diazepam will improve the degree or impact of isavucona